1-(2-(Tetrahydro-2,2-dimethyl-4-(phenylmethyl)-2H-pyran-4-yl)ethyl)piperidine

Base Information

Chemical Name:1-(2-(Tetrahydro-2,2-dimethyl-4-(phenylmethyl)-2H-pyran-4-yl)ethyl)piperidine
CAS No.:130688-21-0
Molecular Formula:C₂₁H₃₃NO
Molecular Weight:315.499
Hs Code.:
DSSTox Substance ID:DTXSID00926852

Synonyms:BRN 4355255;1-(2-(Tetrahydro-2,2-dimethyl-4-(phenylmethyl)-2H-pyran-4-yl)ethyl)piperidine;Piperidine, 1-(2-(tetrahydro-2,2-dimethyl-4-(phenylmethyl)-2H-pyran-4-yl)ethyl)-;130688-21-0;Oprea1_515967;Oprea1_527703;1-[2-(4-benzyl-2,2-dimethyloxan-4-yl)ethyl]piperidine;DTXSID00926852;LS-116177

Suppliers and Price of 1-(2-(Tetrahydro-2,2-dimethyl-4-(phenylmethyl)-2H-pyran-4-yl)ethyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(2-(Tetrahydro-2,2-dimethyl-4-(phenylmethyl)-2H-pyran-4-yl)ethyl)piperidine

Chemical Property:

Vapor Pressure:6.42E-07mmHg at 25°C
Boiling Point:409.6°C at 760 mmHg
Flash Point:120.3°C
Density:0.974g/cm³
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:315.256214676
Heavy Atom Count:23
Complexity:355

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(CCO1)(CCN2CCCCC2)CC3=CC=CC=C3)C

Technology Process of 1-(2-(Tetrahydro-2,2-dimethyl-4-(phenylmethyl)-2H-pyran-4-yl)ethyl)piperidine

There total 4 articles about 1-(2-(Tetrahydro-2,2-dimethyl-4-(phenylmethyl)-2H-pyran-4-yl)ethyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 130688-17-4
2-(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-1-piperidin-1-yl-ethanone

: 130688-21-0
2,2-dimethyl-4-benzyl-4-β-N-piperidylethyltetrahydropyran

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 20h; Heating;
DOI:10.1007/BF00766251

Reference yield:

: 110-89-4
piperidine

: 130688-21-0
2,2-dimethyl-4-benzyl-4-β-N-piperidylethyltetrahydropyran

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / 24 h

2: 53 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 20 h / Heating

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;
DOI:10.1007/BF00766251

Reference yield:

: 109878-51-5
(4-Benzyl-2,2-dimethyl-tetrahydro-pyran-4-yl)-acetic acid

: 130688-21-0
2,2-dimethyl-4-benzyl-4-β-N-piperidylethyltetrahydropyran

Guidance literature:: Multi-step reaction with 3 steps

1: formamide, SOCl₂ / benzene / 1 h / 60 °C

2: diethyl ether / 24 h

3: 53 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 20 h / Heating

With lithium aluminium tetrahydride; thionyl chloride; formamide; In tetrahydrofuran; diethyl ether; benzene;
DOI:10.1007/BF00766251