2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide

Base Information

Chemical Name:2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide
CAS No.:1255188-22-7
Molecular Formula:C₂₄H₂₄ClNO₅
Molecular Weight:441.911
Hs Code.:

Synonyms:2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide

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Chemical Property of 2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide

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Technology Process of 2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide

There total 1 articles about 2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 914454-98-1
2-(2-chloro-6-methoxyphenoxy)ethylamine

: 244123-12-4
2-(2-(benzyloxy)phenoxy)acetic acid

: 1255188-22-7
2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide

Guidance literature:: 2-(2-(benzyloxy)phenoxy)acetic acid; With chloroformic acid ethyl ester; triethylamine; In chloroform; at 0 ℃; for 0.5h;

2-(2-chloro-6-methoxyphenoxy)ethylamine; In chloroform; at 20 ℃; for 3h;
DOI:10.1016/j.bmc.2010.08.002

Reference yield: 80.0%

: 1255188-22-7
2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide

: 1255187-91-7
2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxyphenoxy)ethyl)ethanamine

Guidance literature:: 2-(2-(benzyloxy)phenoxy)-N-(2-(2-chloro-6-methoxy phenoxy)ethyl)acetamide; With dimethylsulfide borane complex; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 60 ℃; for 1h;

With sodium hydroxide; In water;
DOI:10.1016/j.bmc.2010.08.002