2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole

Base Information

• Chemical Name: 2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole
• CAS No.: 1334688-21-9
• Molecular Formula: C₂₂H₂₅NO₂SSi
• Molecular Weight: 395.598
• Mol file: 1334688-21-9.mol

Synonyms:2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole

Chemical Property of 2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole

There total 3 articles about 2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C22H27NO2SSi (1239131-17-9) → 2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole (1334688-21-9)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; at 160 ℃; for 48h; Inert atmosphere;

DOI:10.1021/ol202283d

Reference yield: 56.0%

C22H27NO2SSi (1334688-07-1) → 2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole (1334688-21-9)

Guidance literature:

With iron(III) chloride; iron(II) acetylacetonate; In chlorobenzene; at 150 ℃; for 5h; Microwave irradiation; Sealed tube;

DOI:10.1021/acs.joc.7b02672

Reference yield: 29.0%

C22H27NO2SSi (1334688-18-4) → 2-tosyl-4-(trimethylsilyl)-2,3-dihydro-1H-benzo[f]isoindole (1334688-21-9)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; at 160 ℃; for 48h; Inert atmosphere;

DOI:10.1021/ol202283d

upstream raw materials:

C₂₂H₂₇NO₂SSi

C₂₂H₂₇NO₂SSi

C₂₂H₂₇NO₂SSi

Downstream raw materials:

4-bromo-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole

2-(4-toluenesulfonyl)-2,3-dihydro-1H-benzo[f]isoindole