S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate

Base Information

• Chemical Name: S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate
• CAS No.: 945904-65-4
• Molecular Formula: C₁₃H₁₁NOS
• Molecular Weight: 230.291
• Mol file: 945904-65-4.mol

Synonyms:S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate

Chemical Property of S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate

There total 2 articles about S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2,2'-dipyridyldisulphide (2127-03-9) + -p-toluic acid (110625-18-8) → S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate (945904-65-4)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 16h;

DOI:10.1021/jo070593x

Reference yield:

C7(13)CH7N (70026-38-9) → S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate (945904-65-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.41 g / H₂SO₄; water / 2 h / 150 °C

2: 96 percent / PPh₃ / tetrahydrofuran / 16 h / 20 °C

With sulfuric acid; water; triphenylphosphine; In tetrahydrofuran;

DOI:10.1021/jo070593x

Reference yield: 45.0%

S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate (945904-65-4) + 10-(dibutylboryl)-5-mesityl-1-[4-[2-(trimethylsilyl)ethynyl]benzoyl]dipyrromethane → 10-(dibutylboryl)-5-mesityl-1-(4-methylbenzoyl-carbonyl-13C)-9-[4-[2-(trimethylsilyl)ethynyl]benzoyl]dipyrromethane

Guidance literature:

10-(dibutylboryl)-5-mesityl-1-[4-[2-(trimethylsilyl)ethynyl]benzoyl]dipyrromethane; With ethylmagnesium bromide; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; at 20 ℃; for 0.166667h;

S-2-pyridyl 4-methylbenzo-carbonyl-13C-thioate; In tetrahydrofuran; at 20 ℃; for 2h; Further stages.;

DOI:10.1021/jo070593x

upstream raw materials:

2,2'-dipyridyldisulphide

-p-toluic acid

C₇⁽¹³⁾CH₇N