Technology Process of C27H43IO4Si
There total 13 articles about C27H43IO4Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C19H30O2Si;
With
tin(IV) chloride;
In
dichloromethane;
at -78 ℃;
for 0.75h;
(2R,3E)-4-iodo-2-methyl-2-(triethylsilyloxy)but-3-enal;
In
dichloromethane;
at -78 ℃;
for 3h;
With
water; sodium hydrogencarbonate; triethylamine;
In
dichloromethane;
at -78 - 20 ℃;
DOI:10.1016/j.tet.2011.07.066
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 2,6-dimethylpyridine / dichloromethane / 1.5 h / -78 - 20 °C
2.1: pyridinium p-toluenesulfonate / methanol; dichloromethane / 0.25 h
3.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 1 h
4.1: tin(IV) chloride / dichloromethane / 0.75 h / -78 °C
4.2: 3 h / -78 °C
4.3: -78 - 20 °C
With
2,6-dimethylpyridine; pyridinium p-toluenesulfonate; tin(IV) chloride; sodium hydrogencarbonate; Dess-Martin periodane;
In
methanol; dichloromethane;
4.1: Sakurai reaction / 4.2: Sakurai reaction;
DOI:10.1016/j.tet.2011.07.066
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: tetrakis(triphenylphosphine) palladium(0); tri-n-butyl-tin hydride / tetrahydrofuran / 0.33 h
2.1: pyridinium p-toluenesulfonate; toluene-4-sulfonic acid / methanol / 2 h
3.1: 2,6-dimethylpyridine / dichloromethane / 1.5 h / -78 - 20 °C
4.1: pyridinium p-toluenesulfonate / methanol; dichloromethane / 0.25 h
5.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 1 h
6.1: tin(IV) chloride / dichloromethane / 0.75 h / -78 °C
6.2: 3 h / -78 °C
6.3: -78 - 20 °C
With
2,6-dimethylpyridine; tetrakis(triphenylphosphine) palladium(0); tri-n-butyl-tin hydride; pyridinium p-toluenesulfonate; tin(IV) chloride; sodium hydrogencarbonate; Dess-Martin periodane; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; dichloromethane;
6.1: Sakurai reaction / 6.2: Sakurai reaction;
DOI:10.1016/j.tet.2011.07.066
