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Technology Process of Conivaptan

Conivaptan

Base Information
  • Chemical Name:Conivaptan
  • CAS No.:210101-16-9
  • Molecular Formula:C32H26 N4 O2
  • Molecular Weight:498.583
  • Hs Code.:
  • UNII:0NJ98Y462X
  • DSSTox Substance ID:DTXSID80175220
  • Nikkaji Number:J818.497F
  • Wikipedia:Conivaptan
  • Wikidata:Q5161126
  • NCI Thesaurus Code:C74428
  • RXCUI:302285
  • Pharos Ligand ID:HNY8CP78CUV8
  • Metabolomics Workbench ID:43148
  • ChEMBL ID:CHEMBL1755
  • Mol file:210101-16-9.mol
Conivaptan

Synonyms:(1,1'-biphenyl)-2-carboxamide, N-(4-((4,5-dihydro-2-methylimidazo(4,5-D)(1)benzazepin-6(1H)-yl)carbonyl)phenyl)-;(1,1'-biphenyl)-2-carboxamide, N-(4-((4,5-dihydro-2-methylimidazo(4,5-D)(1)benzazepin-6(1H)-yl)carbonyl)phenyl)-, monohydrochloride;4''-((4,5-dihydro-2-methylimidazo(4,5-D)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide;CI-1025;conivaptan;conivaptan HCl;conivaptan hydrochloride;Vaprisol;YM 087;YM-087;YM087

Suppliers and Price of Conivaptan
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Biosynth Carbosynth
  • Conivaptan
  • 250 mg
  • $ 400.00
  • Biosynth Carbosynth
  • Conivaptan
  • 100 mg
  • $ 300.00
  • Biosynth Carbosynth
  • Conivaptan
  • 50 mg
  • $ 200.00
  • Biosynth Carbosynth
  • Conivaptan
  • 25 mg
  • $ 125.00
  • Biosynth Carbosynth
  • Conivaptan
  • 10 mg
  • $ 70.00
Total 13 raw suppliers
Chemical Property of Conivaptan
Chemical Property:
  • Vapor Pressure:1.89E-22mmHg at 25°C 
  • Boiling Point:751.2°C at 760 mmHg 
  • Flash Point:408.1°C 
  • PSA：78.09000 
  • Density:1.298g/cm3 
  • LogP:6.64530 
  • XLogP3:5.7
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:4
  • Exact Mass:498.20557608
  • Heavy Atom Count:38
  • Complexity:820
Purity/Quality:

99% *data from raw suppliers

Conivaptan *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1=NC2=C(N1)CCN(C3=CC=CC=C32)C(=O)C4=CC=C(C=C4)NC(=O)C5=CC=CC=C5C6=CC=CC=C6
  • Recent ClinicalTrials:Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients
  • Recent EU Clinical Trials:A Phase 2, Randomized, Double Blind, Placebo Controlled, Dose Escalation Study to Assess the Safety and Effects of Intravenous Conivaptan on the Hepatic Hemodynamic Response in Stable Euvolemic or Hypervolemic Cirrhotic Patients
  • Description Conivaptan, a vasopressin antagonist, was discovered and developed by Yamanouchi for the treatment of hyponatraeum associated with congestive heart failure.
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