(2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol

Base Information

• Chemical Name: (2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol
• CAS No.: 1101117-83-2
• Molecular Formula: C₂₈H₂₈O₃
• Molecular Weight: 412.529
• Mol file: 1101117-83-2.mol

Synonyms:(2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol

Chemical Property of (2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol

There total 1 articles about (2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C9H14O3 + trityl chloride (76-83-5) → (2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol (1101117-83-2)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; regioselective reaction;

DOI:10.1039/b810654a

Reference yield: 95.0%

(2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol (1101117-83-2) + trichloroacetonitrile (545-06-2) → (2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-yl 2,2,2-trichloroacetimidate (1101117-86-5)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1039/b810654a

Reference yield: 86.6%

(2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol (1101117-83-2) + allyl bromide (106-95-6) → (2R,3R,6S)-2-allyl-3-allyloxy-6-(trityloxymethyl)-3,6-dihydro-2H-pyran (1101117-84-3)

Guidance literature:

(2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-ol; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; Reflux;

allyl bromide; In tetrahydrofuran; mineral oil; at 20 ℃; Reflux;

DOI:10.1039/b810654a

upstream raw materials:

trityl chloride

Downstream raw materials:

(2R,3R,6S)-2-allyl-3-allyloxy-6-(trityloxymethyl)-3,6-dihydro-2H-pyran

(2R,3R,6S)-2-allyl-6-(trityloxymethyl)-3,6-dihydro-2H-pyran-3-yl 2,2,2-trichloroacetimidate