(R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl (2S,3R)-2-benzyloxy-3-hydroxybutanamide

Base Information

Chemical Name:(R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl (2S,3R)-2-benzyloxy-3-hydroxybutanamide
CAS No.:1234714-28-3
Molecular Formula:C₂₇H₃₃NO₄
Molecular Weight:435.563
Hs Code.:

Synonyms:(R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl (2S,3R)-2-benzyloxy-3-hydroxybutanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl (2S,3R)-2-benzyloxy-3-hydroxybutanamide

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Technology Process of (R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl (2S,3R)-2-benzyloxy-3-hydroxybutanamide

There total 1 articles about (R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl (2S,3R)-2-benzyloxy-3-hydroxybutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1234713-85-9
(R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl 2-benzyloxyacetamide

: 75-07-0,9002-91-9
acetaldehyde

: 1234714-28-3
(R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl (2S,3R)-2-benzyloxy-3-hydroxybutanamide

: C₂₇H₃₃NO₄

Guidance literature:: (R)-N-tert-butoxy-N-1'-(1''-naphthyl)ethyl 2-benzyloxyacetamide; With potassium hexamethylsilazane; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

acetaldehyde; In tetrahydrofuran; at -78 ℃;

In tetrahydrofuran; pH=7; optical yield given as %de; diastereoselective reaction; phosphate buffer;
DOI:10.1016/j.tet.2010.03.105