6-(benzyloxy)hex-1-en-4-yne

Base Information

• Chemical Name: 6-(benzyloxy)hex-1-en-4-yne
• CAS No.: 172788-00-0
• Molecular Formula: C₁₃H₁₄O
• Molecular Weight: 186.254
• Mol file: 172788-00-0.mol

Synonyms:6-(benzyloxy)hex-1-en-4-yne

Chemical Property of 6-(benzyloxy)hex-1-en-4-yne

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(benzyloxy)hex-1-en-4-yne

There total 2 articles about 6-(benzyloxy)hex-1-en-4-yne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Benzyl propargyl ether (4039-82-1) + allyl bromide (106-95-6) → 6-(benzyloxy)hex-1-en-4-yne (172788-00-0)

Guidance literature:

With copper(l) iodide; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 0 ℃; for 6h;

DOI:10.1021/jo00125a039

Reference yield: 68.0%

hex-5-en-2-yn-1-ol (2749-86-2) + benzyl alcohol (100-51-6,185532-71-2) → 6-(benzyloxy)hex-1-en-4-yne (172788-00-0)

Guidance literature:

hex-5-en-2-yn-1-ol; With dicobalt octacarbonyl; In dichloromethane; at 20 ℃; for 1h;

benzyl alcohol; With boron trifluoride diethyl etherate; In dichloromethane; at -20 ℃; for 1h;

With ammonium cerium(IV) nitrate; In acetone; at 0 ℃; for 0.0833333h;

DOI:10.1016/S0040-4039(00)01756-1

Reference yield: 74.0%

6-(benzyloxy)hex-1-en-4-yne (172788-00-0) → 6-(benzyloxy)-1,2-epoxy-4-hexyne (172788-01-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 16h;

DOI:10.1021/jo00125a039

upstream raw materials:

Benzyl propargyl ether

allyl bromide

hex-5-en-2-yn-1-ol

benzyl alcohol

Downstream raw materials:

6-(benzyloxy)-1,2-epoxy-4-hexyne

6-(benzyloxy)-1,2-epithio-4-hexyne

5-<(benzyloxy)methyl>-2,3-dihydro-4-iodo-2-(iodomethyl)thiophene