4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether

Base Information

• Chemical Name: 4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether
• CAS No.: 1225289-38-2
• Molecular Formula: C₁₉H₁₃F₃O
• Molecular Weight: 314.307
• Mol file: 1225289-38-2.mol

Synonyms:4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether

Chemical Property of 4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether

There total 1 articles about 4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

propargyl bromide (106-96-7) + 1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol (186143-62-4) → 4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether (1225289-38-2)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; sodium hydroxide; In dichloromethane; water; at 0 - 20 ℃;

DOI:10.1039/b926192c

Reference yield:

4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether (1225289-38-2) + diphenyl acetylene (501-65-5) → 5-trifluoromethyl-3,3,6,7-tetraphenyl-1,3-dihydroisobenzofuran (1225289-57-5) + C38H26F6O2 + C38H26F6O2 + 4,4,4-trifluoro-1,1-diphenylbut-2-ynyl 2,3,4,5-tetraphenylbenzyl ether

Guidance literature:

With rhodium(III) chloride trihydrate; N-ethyl-N,N-diisopropylamine; at 130 ℃; for 2h; neat (no solvent);

DOI:10.1039/b926192c

upstream raw materials:

propargyl bromide

1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol

Downstream raw materials:

5-trifluoromethyl-3,3,6,7-tetraphenyl-1,3-dihydroisobenzofuran