Technology Process of althiomycin
There total 19 articles about althiomycin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 62.3 percent / t-butyl nitrite, 4,67M HCl / tetrahydrofuran; dimethylformamide / 3 h / -30 °C
2: dimethylformamide / 3 h / Ambient temperature
With
hydrogenchloride; tert.-butylnitrite;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.58.352
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 89.7 percent / 100percent hydrazine hydrate / dimethylformamide / 18 h / 5 °C
2: 62.3 percent / t-butyl nitrite, 4,67M HCl / tetrahydrofuran; dimethylformamide / 3 h / -30 °C
3: dimethylformamide / 3 h / Ambient temperature
With
hydrogenchloride; tert.-butylnitrite; hydrazine hydrate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.58.352
- Guidance literature:
-
Multi-step reaction with 5 steps
1: CHCl3; tetrahydrofuran / 6 h / 0 °C / Irradiation
2: CHCl3 / 2.5 h
3: 97.6 percent / dimethylsulfoxide / 168 h / Ambient temperature
4: HF / various solvent(s) / 0.33 h / 0 °C
5: dimethylformamide / 3 h / Ambient temperature
With
hydrogen fluoride;
In
tetrahydrofuran; chloroform; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.58.352
