Technology Process of 3,8-bis(benzyloxy)-2,9-dimethoxy-6,6-dimethyl-6H-benzo[c]chromene
There total 4 articles about 3,8-bis(benzyloxy)-2,9-dimethoxy-6,6-dimethyl-6H-benzo[c]chromene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; caesium carbonate; triphenylphosphine;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 24h;
Inert atmosphere;
DOI:10.1021/ol2032625
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: silica gel; pyridinium chlorochromate / dichloromethane / 2 h / 20 °C / Inert atmosphere
2.1: iodine; magnesium / diethyl ether / Inert atmosphere
2.2: 3 h / -10 °C / Inert atmosphere
2.3: Inert atmosphere
3.1: palladium diacetate; caesium carbonate; triphenylphosphine / N,N-dimethyl-formamide / 24 h / 80 °C / Inert atmosphere
With
iodine; palladium diacetate; silica gel; caesium carbonate; magnesium; triphenylphosphine; pyridinium chlorochromate;
In
diethyl ether; dichloromethane; N,N-dimethyl-formamide;
2.2: Grignard reaction;
DOI:10.1021/ol2032625
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: iodine; magnesium / diethyl ether / Inert atmosphere
1.2: 3 h / -10 °C / Inert atmosphere
1.3: Inert atmosphere
2.1: palladium diacetate; caesium carbonate; triphenylphosphine / N,N-dimethyl-formamide / 24 h / 80 °C / Inert atmosphere
With
iodine; palladium diacetate; caesium carbonate; magnesium; triphenylphosphine;
In
diethyl ether; N,N-dimethyl-formamide;
1.2: Grignard reaction;
DOI:10.1021/ol2032625
![2-[5-(benzyloxy)-2-bromo-4-methoxyphenyl]propan-2-ol](/Databaselist/images/loading.webp)
