3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone

Base Information

• Chemical Name: 3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone
• CAS No.: 543731-08-4
• Molecular Formula: C₃₀H₄₀N₂O₃
• Molecular Weight: 476.659
• Mol file: 543731-08-4.mol

Synonyms:3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone

Chemical Property of 3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone

There total 1 articles about 3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

1-(β-aminoethyl)-3-(benzyloxy)-2-methyl-4(1H)-pyridinone (149457-89-6) + 3,5-di-t-butyl-4-hydroxybenzaldehyde (1620-98-0) → 3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone (543731-08-4)

Guidance literature:

With sodium cyanoborohydride; In methanol;

DOI:10.1016/S0960-894X(02)00698-4

Reference yield: 96.0%

3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone (543731-08-4) → 1-[2-(3,5-Di-tert-butyl-4-hydroxybenzylamino)ethyl]-3-hydroxy-2-methyl-4(1H)-pyridinone dihydrochloride

Guidance literature:

With hydrogenchloride; palladium-carbon; In CH₂Cl₂and; diethyl ether; ethanol; ethyl acetate;

Reference yield: 96.0%

3-Benzyloxy-1-[2-(3,5-di-tert-butyl-4-hydroxybenzylamino)ethyl]-2-methyl-4(1H)-pyridinone (543731-08-4) → 1-[2-(3,5-di-tert-butyl-4-hydroxy-benzylamino)-ethyl]-3-hydroxy-2-methyl-1H-pyridin-4-one

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr;

DOI:10.1016/S0960-894X(02)00698-4

upstream raw materials:

1-(β-aminoethyl)-3-(benzyloxy)-2-methyl-4(1H)-pyridinone

3,5-di-t-butyl-4-hydroxybenzaldehyde