[1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid

Base Information

• Chemical Name: [1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid
• CAS No.: 209737-00-8
• Molecular Formula: C₂₂H₂₆N₆O₄S
• Molecular Weight: 470.552

Synonyms:[1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid

Chemical Property of [1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid

Chemical Property:

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Technology Process of [1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid

There total 1 articles about [1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C25H30N6O4S (209737-65-5) → C22H26N6O4S + [1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid (209737-00-8)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 2h;

DOI:10.1016/j.bmcl.2007.07.057

Reference yield:

[1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid (209737-00-8) → [1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)-amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxamide

Guidance literature:

In methanol;

Reference yield:

[1S-[1α,2β,3β,4α(trans)]]-2,3-dihydroxy-4-[7-[(2-phenylcyclopropyl)amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboxylic acid (209737-00-8) → [1S-[1α,2β,3β,4α(trans)]]-2,3-Dihydroxy-N-(2-Hydroxyethyl)-4-[5-[[(4-trifluoromethyl)phenyl]thio]-7-[(2-phenylcyclopropyl)amino]-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-cyclopentanecarboamide

Guidance literature:

upstream raw materials:

C₂₅H₃₀N₆O₄S

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