(S)-2-{(S)-2-[(S)-2-(2-Benzyloxycarbonyl-acetylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-4-methylsulfanyl-butyric acid methyl ester

Base Information

• Chemical Name: (S)-2-{(S)-2-[(S)-2-(2-Benzyloxycarbonyl-acetylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-4-methylsulfanyl-butyric acid methyl ester
• CAS No.: 182558-01-6
• Molecular Formula: C₂₆H₃₉N₃O₇S
• Molecular Weight: 537.678
• Mol file: 182558-01-6.mol

Synonyms:(S)-2-{(S)-2-[(S)-2-(2-Benzyloxycarbonyl-acetylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-4-methylsulfanyl-butyric acid methyl ester

Chemical Property of (S)-2-{(S)-2-[(S)-2-(2-Benzyloxycarbonyl-acetylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-4-methylsulfanyl-butyric acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (S)-2-{(S)-2-[(S)-2-(2-Benzyloxycarbonyl-acetylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-4-methylsulfanyl-butyric acid methyl ester

There total 1 articles about (S)-2-{(S)-2-[(S)-2-(2-Benzyloxycarbonyl-acetylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-4-methylsulfanyl-butyric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

malonic acid dibenzyl ester (15014-25-2) + 2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-methyl-butyrylamino]-4-methylsulfanyl-butyric acid methyl ester → (S)-2-{(S)-2-[(S)-2-(2-Benzyloxycarbonyl-acetylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-4-methylsulfanyl-butyric acid methyl ester (182558-01-6)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; acetonitrile; for 20h; Ambient temperature;

DOI:10.1021/jm960190h

upstream raw materials:

malonic acid dibenzyl ester