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Technology Process of 4,4'-(Furan-2,5-diyl)dibenzimidamide dihydrochloride

4,4'-(Furan-2,5-diyl)dibenzimidamide dihydrochloride

Base Information
  • Chemical Name:4,4'-(Furan-2,5-diyl)dibenzimidamide dihydrochloride
  • CAS No.:55368-40-6
  • Molecular Formula:C18H16 N4 O . 2 Cl H
  • Molecular Weight:0
  • Hs Code.:
  • DSSTox Substance ID:DTXSID90970703
  • Mol file:55368-40-6.mol
4,4'-(Furan-2,5-diyl)dibenzimidamide dihydrochloride

Synonyms:55368-40-6;Furamidine Dihydrochloride;4,4'-(Furan-2,5-diyl)dibenzimidamide dihydrochloride;Furamidine (dihydrochloride);Furamidine HCl;db75-dihydrochloride;SCHEMBL7734063;DTXSID90970703;4,4'-(2,5-Furandiyl)bis-benzenecarboximidamide dihydrochloride;AKOS025147335;SB60935;MS-26130;HY-110137;CS-0032994;4,4'-(Furan-2,5-diyl)dibenzimidamidedihydrochloride;DB 75, DB75, NSC 305831, WR199385;4,4'-(2,5-Furandiyl)dibenzenecarboximidamide dihydrochloride;4-[5-(4-carbamimidoylphenyl)furan-2-yl]benzenecarboximidamide;dihydrochloride

Suppliers and Price of 4,4'-(Furan-2,5-diyl)dibenzimidamide dihydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Furamidine dihydrochloride
  • 10mg
  • $ 432.00
  • TRC
  • FuramidineDihydrochloride
  • 50mg
  • $ 1135.00
  • Tocris
  • Furamidinedihydrochloride ≥98%(HPLC)
  • 5
  • $ 96.00
  • Tocris
  • Furamidinedihydrochloride ≥98%(HPLC)
  • 25
  • $ 364.00
  • Medical Isotopes, Inc.
  • FuramidineDiHCl
  • 50 mg
  • $ 2200.00
  • CSNpharm
  • Furamidine2HCl
  • 5mg
  • $ 326.00
  • ChemScene
  • Furamidinedihydrochloride ≥98.0%
  • 5mg
  • $ 350.00
  • Cayman Chemical
  • Furamidine (hydrochloride) ≥98%
  • 10mg
  • $ 150.00
  • Cayman Chemical
  • Furamidine (hydrochloride) ≥98%
  • 5mg
  • $ 82.00
  • Cayman Chemical
  • Furamidine (hydrochloride) ≥98%
  • 1mg
  • $ 28.00
Total 11 raw suppliers
Chemical Property of 4,4'-(Furan-2,5-diyl)dibenzimidamide dihydrochloride
Chemical Property:
  • Melting Point:400-401 °C(Solv: ethanol (64-17-5)) 
  • PSA：112.88000 
  • LogP:5.58380 
  • Storage Temp.:-20°C 
  • Solubility.:DMSO (Slightly), Methanol (Slightly) 
  • Hydrogen Bond Donor Count:6
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:4
  • Exact Mass:376.0857666
  • Heavy Atom Count:25
  • Complexity:396
Purity/Quality:

98%,99%, *data from raw suppliers

Furamidine dihydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1=CC(=CC=C1C2=CC=C(O2)C3=CC=C(C=C3)C(=N)N)C(=N)N.Cl.Cl
  • Description Furamidinedihydrochloride (DB75dihydrochloride) is a selective and cell-permeable inhibitor of protein arginine methyltransferase 1 (PRMT1) with IC50 of 9.4 μM. Furamidinedihydrochloride is more selective for PRMlookchemT1 than PRMT5, PRMT6 and PRMT4(CARM1) (IC50 of 166μM, 283μM and >400μM, respectively). Furamidinedihydrochloride is a potent, reversible and competitive inhibitor of tyrosyl DNA phosphodiesterase 1 (TDP-1).
  • Uses Furamidine is a diphenylfuran compound belonging to an important class of antimicrobial and antiparasitic agents. Furamidine and its analogues also display antitumor activities and showed antiproliferative activities against various tumor cell lines.
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