2-(2-Thiazolylazo)-p-cresol

Base Information

• Chemical Name: 2-(2-Thiazolylazo)-p-cresol
• CAS No.: 1823-44-5
• Molecular Formula: C10H9N3OS
• Molecular Weight: 219.267
• Hs Code.: 2934100090
• European Community (EC) Number: 625-494-0
• DSSTox Substance ID: DTXSID601310791
• Nikkaji Number: J7.783F
• ChEMBL ID: CHEMBL1318526
• Mol file: 1823-44-5.mol

Synonyms:2-(2-Thiazolylazo)-p-cresol;1823-44-5;4-methyl-2-(1,3-thiazol-2-yldiazenyl)phenol;(e)-4-methyl-2-(thiazol-2-yldiazenyl)phenol;2-(Thiazolylazo)-p-cresol;MLS001360007;96627-59-7;SMR001224337;Phenol, 4-methyl-2-[2-(2-thiazolyl)diazenyl]-;(6E)-4-methyl-6-(2-thiazolylhydrazinylidene)-1-cyclohexa-2,4-dienone;(6E)-4-methyl-6-(1,3-thiazol-2-ylhydrazinylidene)cyclohexa-2,4-dien-1-one;TAC[Dotite];Phenol, 4-methyl-2-(2-thiazolylazo)-;4-Methyl-2-[(E)-1,3-thiazol-2-yldiazenyl]phenol;SCHEMBL5728387;CHEMBL1318526;BDBM66034;cid_9576957;DTXSID601310791;HMS3066O16;MFCD00005323;2-(2-Thiazolylazo)-p-cresol, 97%;AKOS015912871;GS-6404;2-(2-THIAZOLYLAZO)-PARA-CRESOL;NCGC00247287-01;FT-0618997;H10346;A812685;J-011667;4-Methyl-2-[(E)-1,3-thiazol-2-yldiazenyl]phenol #;4-methyl-2-[(E)-2-(1,3-thiazol-2-yl)diazen-1-yl]phenol;(6E)-4-methyl-6-(thiazol-2-ylhydrazono)cyclohexa-2,4-dien-1-one

Chemical Property of 2-(2-Thiazolylazo)-p-cresol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 130-132 °C(lit.)
• Refractive Index: 1.681
• Boiling Point: 392.6 °C at 760 mmHg
• PKA: 8.76±0.48(Predicted)
• Flash Point: 191.2 °C
• PSA: 86.08000
• Density: 1.35 g/cm³
• LogP: 3.57250
• Storage Temp.: 2-8°C
• Solubility.: soluble50mg/mL, clear, red to red-brown (ethanol:CHCl3 (1:1))
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 219.04663309
• Heavy Atom Count: 15
• Complexity: 237

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2-Thiazolylazo)-p-cresol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)O)N=NC2=NC=CS2
• Uses: 2-(2-Thiazolylazo)-p-cresol is a heterocyclic azo-dye2, has been used:as iron binding ligand during determination of iron speciation in seawater by cathodic stripping voltammetryin spectrophotometric determination of vanadium, titanium, lead, indium and nickelas as a spectrophotometric reagent in the determination of uranium in mine drainage water samples

Technology Process of 2-(2-Thiazolylazo)-p-cresol

There total 3 articles about 2-(2-Thiazolylazo)-p-cresol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-methyl-2-(2-(thiazol-2-yl)-hydrazinyl)-phenol → 4-methyl-2-(thiazol-2-yl-diazenyl)phenol (1823-44-5)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; acetic acid; titanium(III) chloride; hydrogen bromide; In methanol; at 20 ℃;

DOI:10.1021/ja074413c

Reference yield:

p-cresol (106-44-5) → 4-methyl-2-(thiazol-2-yl-diazenyl)phenol (1823-44-5)

Guidance literature:

Reference yield:

→ 4-methyl-2-(thiazol-2-yl-diazenyl)phenol (1823-44-5)

Guidance literature:

Diazot. 2-Aminothiazol, 4-Methylphenol, wss. HCl (0grad);

upstream raw materials:

p-cresol

Downstream raw materials:

[RuCl(CO)(PPh₃)(2-(2-thiazolato)cresol(-H))]

Refernces