Coelonin

Base Information

• Chemical Name: Coelonin
• CAS No.: 82344-82-9
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 242.274
• European Community (EC) Number: 804-744-4
• ChEMBL ID: CHEMBL560627
• DSSTox Substance ID: DTXSID801319163
• Metabolomics Workbench ID: 129701,142813
• Nikkaji Number: J794.529I
• Wikidata: Q104396774
• Mol file: 82344-82-9.mol

Synonyms:coelonin;82344-82-9;4-methoxy-9,10-dihydrophenanthrene-2,7-diol;CHEMBL560627;DTXSID801319163;HY-N8884;AKOS040761520;Coelonin, >=95% (LC/MS-ELSD);FS-7908;CS-0149296

Chemical Property of Coelonin

Chemical Property:

• PSA: 49.69000
• LogP: 2.87200
• Storage Temp.: ?20°C
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 242.094294304
• Heavy Atom Count: 18
• Complexity: 294

Purity/Quality:

95% ^*data from raw suppliers

Coelonin ^*data from reagent suppliers

Safty Information:

• Hazard Codes: N
• Statements: 50
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC2=C1C3=C(CC2)C=C(C=C3)O)O
• Uses: Coelonin is a stilbenoid isolated from the roots of Cyrtopodium paniculatum which displays cytotoxic actiity.

Technology Process of Coelonin

There total 1 articles about Coelonin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-4-(benzyloxy)-2-(3-(benzyloxy)-5-methoxystyryl)-1-iodobenzene → lusianthridin (87530-30-1) + coelonin (82344-82-9)

Guidance literature:

(Z)-4-(benzyloxy)-2-(3-(benzyloxy)-5-methoxystyryl)-1-iodobenzene; With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 100 ℃; for 16h; Inert atmosphere;

With palladium 10% on activated carbon; hydrogen; acetic acid; In tetrahydrofuran; at 20 ℃; for 48h; Overall yield = 11.5 g;

Reference yield: 82.0%

coelonin (82344-82-9) → blestriarene A (126721-53-7,120090-80-4)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; copper(II) hydroxichloride; In dichloromethane; at 20 ℃; for 4h;

Downstream raw materials:

blestriarene A