2-(Z)-tert-butyldiphenylsilylmethylidene-3,4-diphenyl-6-methoxy-2H-1-benzopyran

Base Information

• Chemical Name: 2-(Z)-tert-butyldiphenylsilylmethylidene-3,4-diphenyl-6-methoxy-2H-1-benzopyran
• CAS No.: 1372625-26-7
• Molecular Formula: C₃₉H₃₆O₂Si
• Molecular Weight: 564.799
• Mol file: 1372625-26-7.mol

Synonyms:2-(Z)-tert-butyldiphenylsilylmethylidene-3,4-diphenyl-6-methoxy-2H-1-benzopyran

Chemical Property of 2-(Z)-tert-butyldiphenylsilylmethylidene-3,4-diphenyl-6-methoxy-2H-1-benzopyran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(Z)-tert-butyldiphenylsilylmethylidene-3,4-diphenyl-6-methoxy-2H-1-benzopyran

There total 2 articles about 2-(Z)-tert-butyldiphenylsilylmethylidene-3,4-diphenyl-6-methoxy-2H-1-benzopyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-(4-methoxyphenoxy)-1-tert-butyldiphenylsilylacetylene (1372625-10-9) + diphenyl acetylene (501-65-5) → 2-(Z)-tert-butyldiphenylsilylmethylidene-3,4-diphenyl-6-methoxy-2H-1-benzopyran (1372625-26-7)

Guidance literature:

With palladium diacetate; zinc; tricyclohexylphosphine; In toluene; at 90 ℃; for 6h; Inert atmosphere;

DOI:10.1021/ja301588z

Reference yield:

1-(1,2-dichloroethenyloxy)-4-methoxybenzene (1188296-81-2) + tert-butylchlorodiphenylsilane (58479-61-1) → 2-(Z)-tert-butyldiphenylsilylmethylidene-3,4-diphenyl-6-methoxy-2H-1-benzopyran (1372625-26-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1.17 h / -78 - 20 °C / Inert atmosphere

1.2: 16 h / -78 - 20 °C / Inert atmosphere

2.1: palladium diacetate; zinc; tricyclohexylphosphine / toluene / 6 h / 90 °C / Inert atmosphere

With n-butyllithium; palladium diacetate; zinc; tricyclohexylphosphine; In tetrahydrofuran; hexane; toluene;

DOI:10.1021/ja301588z

upstream raw materials:

1-(1,2-dichloroethenyloxy)-4-methoxybenzene

tert-butylchlorodiphenylsilane

2-(4-methoxyphenoxy)-1-tert-butyldiphenylsilylacetylene

diphenyl acetylene