2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine

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Chemical Name:2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine
CAS No.:1000265-04-2
Molecular Formula:C₂₄H₂₃FN₄O₂
Molecular Weight:418.471
Hs Code.:

Synonyms:2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine

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Chemical Property of 2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine

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Technology Process of 2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine

There total 3 articles about 2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 1000267-51-5
2-(2-formyl-3-methylphenoxy)acetamide

: 119072-54-7,2769-71-3
2,6-dimethylphenyl isonitrile

: 21717-96-4
2-amino-5-fluoropyridine

: 1000265-04-2
2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine

Guidance literature:: 2-(2-formyl-3-methylphenoxy)acetamide; 2-amino-5-fluoropyridine; In ethanol; at 20 ℃; Inert atmosphere;

2,6-dimethylphenyl isonitrile; With perchloric acid; In ethanol; at 20 ℃; for 20h; Inert atmosphere;

Reference yield:

: 526-75-0
2,3-Dimethylphenol

: 1000265-04-2
2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; paraffin oil / 0.75 h / 20 °C

1.2: 20 °C

2.1: dipotassium peroxodisulfate; copper(ll) sulfate pentahydrate / acetonitrile; water / 2 h / Reflux

3.1: ethanol / 20 °C / Inert atmosphere

3.2: 20 h / 20 °C / Inert atmosphere

With dipotassium peroxodisulfate; copper(ll) sulfate pentahydrate; sodium hydride; In ethanol; water; N,N-dimethyl-formamide; acetonitrile; paraffin oil;

Reference yield:

: 35368-58-2
2-(2,3-dimethylphenoxy)acetamide

: 1000265-04-2
2-[2-(aminocarbonylmethoxy)-6-methylphenyl]-3-(2,6-dimethylphenylamino)-6-fluoroimidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: dipotassium peroxodisulfate; copper(ll) sulfate pentahydrate / acetonitrile; water / 2 h / Reflux

2.1: ethanol / 20 °C / Inert atmosphere

2.2: 20 h / 20 °C / Inert atmosphere

With dipotassium peroxodisulfate; copper(ll) sulfate pentahydrate; In ethanol; water; acetonitrile;