(1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate

Base Information

Chemical Name:(1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate
CAS No.:888725-65-3
Molecular Formula:C₁₈H₂₄F₃NO₄
Molecular Weight:375.388
Hs Code.:

Synonyms:(1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate

Suppliers and Price of (1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate

There total 4 articles about (1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 888725-64-2
(1S,2R)-N-benzyl-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)but-3-en-1-amine

: 888725-65-3
(1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C / ethyl acetate / 5 h / 20 °C

2: 406 mg / aq. NaHCO₃ / tetrahydrofuran / 2 h / 20 °C

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;
DOI:10.1021/jo0601157

Reference yield:

: 135821-68-0
(S)-N-benzyl-2,3-O-isopropylidene-glyceraldimine

: 888725-65-3
(1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 55 percent / In powder / dimethylformamide / 15 h / 20 °C

2: H₂ / Pd/C / ethyl acetate / 5 h / 20 °C

3: 406 mg / aq. NaHCO₃ / tetrahydrofuran / 2 h / 20 °C

With indium; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jo0601157

Reference yield:

: 22323-80-4
(4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde

: 888725-65-3
(1S,2R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(trifluoromethyl)butylcarbamate

Guidance literature:: Multi-step reaction with 4 steps

1: MgSO₄ / CH₂Cl₂ / 20 °C

2: 55 percent / In powder / dimethylformamide / 15 h / 20 °C

3: H₂ / Pd/C / ethyl acetate / 5 h / 20 °C

4: 406 mg / aq. NaHCO₃ / tetrahydrofuran / 2 h / 20 °C

With indium; hydrogen; sodium hydrogencarbonate; magnesium sulfate; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jo0601157