Technology Process of 2-decarboxy-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-PGF1α 11,15-bis(tert-butyldimethylsilyl ether)
There total 1 articles about 2-decarboxy-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-PGF1α 11,15-bis(tert-butyldimethylsilyl ether) which
guide to synthetic route it.
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synthetic route:
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647028-35-1
2-decarboxy-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-PGE1 11,15-bis(tert-butyldimethylsilyl ether)
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647028-36-2
2-decarboxy-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-PGF1β 11,15-bis(tert-butyldimethylsilyl ether)
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647028-37-3
2-decarboxy-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-PGF1α 11,15-bis(tert-butyldimethylsilyl ether)
- Guidance literature:
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2-decarboxy-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-PGE1 11,15-bis(tert-butyldimethylsilyl ether);
With
2,6-di-tert-butyl-4-methyl-phenol; diisobutylaluminium hydride;
In
hexane; toluene;
at -78 - -10 ℃;
for 2h;
With
hydrogenchloride; ammonium chloride;
In
hexane; water; toluene;
pH=< 7;