Propanoic acid,3-[[(S)-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-

Base Information

Chemical Name:Propanoic acid,3-[[(S)-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-
CAS No.:120443-17-6
Molecular Formula:C26H27 Cl N2 O3 S2
Molecular Weight:515.097
Hs Code.:
Mol file:120443-17-6.mol

Synonyms:Propanoicacid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-,[S-(E)]-; L 668018; S-(+)-MK 571

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propanoic acid,3-[[(S)-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-

Chemical Property:

Purity/Quality:

Safty Information:

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Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Propanoic acid,3-[[(S)-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-

There total 29 articles about Propanoic acid,3-[[(S)-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 120443-18-7
(S)-3-(((3-(2-(7-chloroquinolin-2-yl)-(E)-ethenyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propionic acid methyl ester

: 120443-17-6
(+)-MK-571

Guidance literature:: With lithium hydroxide; water; In tetrahydrofuran; at 3 ℃; for 7h;
DOI:10.1021/jo00313a010

Reference yield: 50.0%

: 115104-27-3,115104-52-4,115104-56-8,120443-15-4,120443-18-7,120663-37-8,124601-75-8
3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid methyl ester

: 115104-28-4,120443-16-5,120443-17-6,121702-00-9,135028-15-8,143899-88-1
(+)-L-660,711

Guidance literature:: With lithium hydroxide; water; In 1,2-dimethoxyethane; for 3h; Ambient temperature;

Reference yield:

: 120385-96-8
dimethyl 5-<3-<2-(7-chloro-2-quinolinyl)-(E)-ethenyl>phenyl>-4,6-dithianonanedioate

: 120443-17-6
(+)-MK-571

Guidance literature:: Multi-step reaction with 3 steps

1: Triton X-100 / hydrolysis with Pseudomonas species lipase

2: 93 percent / carbonyldiimidazole (CDI)

3: 88 percent / aq. LiOH / tetrahydrofuran

With lithium hydroxide; 1,1'-carbonyldiimidazole; Triton X-100; In tetrahydrofuran;