(1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate

Base Information

Chemical Name:(1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate
CAS No.:1374648-80-2
Molecular Formula:C₈H₈O₃*C₁₅H₂₂N₂O
Molecular Weight:398.502
Hs Code.:

Synonyms:(1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate

Suppliers and Price of (1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate

Chemical Property:

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Technology Process of (1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate

There total 2 articles about (1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 611-71-2
(R)-Mandelic Acid

: 105310-09-6,96847-54-0,92623-85-3,96847-55-1
milnacipran

: 1374648-80-2
(1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate

Guidance literature:: In water; at 20 - 65 ℃; Product distribution / selectivity;

Reference yield:

: 86181-08-0,101152-94-7,175131-61-0
cis-(±)-1-phenyl-2-(aminomethyl)-N,N-diethylcyclopropanecarboxamide hydrochloride

: 1374648-80-2
(1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / dichloromethane; water / 20 °C / pH 10.5

2: water / 20 - 65 °C

With sodium hydroxide; In dichloromethane; water;