2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate

Base Information

Chemical Name:2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate
CAS No.:326598-37-2
Molecular Formula:C₂₃H₂₀N₂O₅S
Molecular Weight:436.488
Hs Code.:

Synonyms:2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate

Suppliers and Price of 2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate

There total 5 articles about 2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 609-73-4
o-nitroiodobenzene

: 219599-04-9
2-(N-methyl-N-prop-2'-ynylamino)phenyl p-toluenesulfonate

: 326598-37-2
2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate

Guidance literature:: With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; at 20 ℃; for 16h;
DOI:10.1021/jo000826j

Reference yield:

: 1216-96-2
2-aminophenyl p-toluenesulfonate

: 326598-37-2
2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: K₂CO₃ / dimethylformamide / 16 h / 20 °C

1.2: 58 percent / dimethylformamide / 48 h / 80 °C

2.1: K₂CO₃ / dimethylformamide / 16 h / 20 °C

2.2: 83 percent / dimethylformamide / 48 h / 80 °C

3.1: 92 percent / CuI; Et₃N / (PPh₃)2PdCl₂ / 16 h / 20 °C

With copper(l) iodide; potassium carbonate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide;
DOI:10.1021/jo000826j

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 326598-37-2
2-[N-methyl-N-{3'-(2-nitrophenyl)prop-2'-ynyl}]aminophenyl p-toluene sulfonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: Et₃N / CH₂Cl₂

2.1: K₂CO₃ / dimethylformamide / 16 h / 20 °C

2.2: 58 percent / dimethylformamide / 48 h / 80 °C

3.1: K₂CO₃ / dimethylformamide / 16 h / 20 °C

3.2: 83 percent / dimethylformamide / 48 h / 80 °C

4.1: 92 percent / CuI; Et₃N / (PPh₃)2PdCl₂ / 16 h / 20 °C

With copper(l) iodide; potassium carbonate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo000826j