(S)-benzyl 2-((S)-2-cyclopropyl-1-(2-(methylcarbamoyl)-1,3-dithiolan-2-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate

Base Information

• Chemical Name: (S)-benzyl 2-((S)-2-cyclopropyl-1-(2-(methylcarbamoyl)-1,3-dithiolan-2-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate
• CAS No.: 1203455-90-6
• Molecular Formula: C₂₃H₃₁N₃O₄S₂
• Molecular Weight: 477.649
• Mol file: 1203455-90-6.mol

Synonyms:(S)-benzyl 2-((S)-2-cyclopropyl-1-(2-(methylcarbamoyl)-1,3-dithiolan-2-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate

Chemical Property of (S)-benzyl 2-((S)-2-cyclopropyl-1-(2-(methylcarbamoyl)-1,3-dithiolan-2-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (S)-benzyl 2-((S)-2-cyclopropyl-1-(2-(methylcarbamoyl)-1,3-dithiolan-2-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate

There total 1 articles about (S)-benzyl 2-((S)-2-cyclopropyl-1-(2-(methylcarbamoyl)-1,3-dithiolan-2-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-[1-amino-2-cyclopropylethyl]-N-methyl-1,3-dithiolane-2-carboxamide hydrochloride (1203455-88-2) + N-Benzyloxycarbonyl-L-proline (1148-11-4) → (S)-benzyl 2-((S)-2-cyclopropyl-1-(2-(methylcarbamoyl)-1,3-dithiolan-2-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate (1203455-90-6)

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 18h;

Reference yield:

(S)-benzyl 2-((S)-2-cyclopropyl-1-(2-(methylcarbamoyl)-1,3-dithiolan-2-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate (1203455-90-6) → (S)-benzyl 2-((S)-1-cyclopropyl-4-(methylamino)-3,4-dioxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate (1203455-91-7)

Guidance literature:

With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; water; In acetonitrile; for 1h;

upstream raw materials:

(S)-2-[1-amino-2-cyclopropylethyl]-N-methyl-1,3-dithiolane-2-carboxamide hydrochloride

N-Benzyloxycarbonyl-L-proline

Downstream raw materials:

(S)-benzyl 2-((S)-1-cyclopropyl-4-(methylamino)-3,4-dioxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate