C₂₁H₁₉FN₄O₂

Base Information

Chemical Name:C₂₁H₁₉FN₄O₂
CAS No.:1431930-36-7
Molecular Formula:C₂₁H₁₉FN₄O₂
Molecular Weight:378.406
Hs Code.:

C<sub>21</sub>H<sub>19</sub>FN<sub>4</sub>O<sub>2</sub>

Synonyms:C₂₁H₁₉FN₄O₂

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Chemical Property of C₂₁H₁₉FN₄O₂

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Technology Process of C₂₁H₁₉FN₄O₂

There total 6 articles about C₂₁H₁₉FN₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 651734-61-1
2-fluoro-3,5-dimethoxybenzenamine

: 1431930-35-6
C₁₃H₁₀IN₃

: 1431930-36-7
C₂₁H₁₉FN₄O₂

Guidance literature:: With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; at 100 ℃; for 15h;

Reference yield:

: 1431930-27-6
3-(2-methyl-1H-pyrazol-4-yl)-6-nitroquinoline

: 1431930-36-7
C₂₁H₁₉FN₄O₂

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / methanol; tetrahydrofuran / 1.5 h / 20 °C / 2250.23 Torr

2: sodium nitrite; hydrogenchloride; potassium iodide / water / 3.5 h / 0 - 20 °C

3: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; sodium t-butanolate / 15 h / 100 °C

With hydrogenchloride; hydrogen; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; potassium iodide; sodium t-butanolate; sodium nitrite; In tetrahydrofuran; methanol; water;

Reference yield:

: 7101-95-3
3-bromo-6-nitroquinoline

: 1431930-36-7
C₂₁H₁₉FN₄O₂

Guidance literature:: Multi-step reaction with 4 steps

1: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; 1,2-dimethoxyethane / 18 h / Inert atmosphere; Reflux

2: hydrogen / methanol; tetrahydrofuran / 1.5 h / 20 °C / 2250.23 Torr

3: sodium nitrite; hydrogenchloride; potassium iodide / water / 3.5 h / 0 - 20 °C

4: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; sodium t-butanolate / 15 h / 100 °C

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; palladium diacetate; sodium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; potassium iodide; sodium t-butanolate; sodium nitrite; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; water;