4-Hydroxyproline

Base Information

Chemical Name:4-Hydroxyproline
CAS No.:49761-17-3
Molecular Formula:C5H9 N O3
Molecular Weight:131.131
Hs Code.:
NSC Number:524341,122285,206304,206274,206273
DSSTox Substance ID:DTXSID60861573
Nikkaji Number:J4.116E
Wikidata:Q411237
ChEMBL ID:CHEMBL1213475
Mol file:49761-17-3.mol

Synonyms:4 Hydroxyproline;4-Hydroxyproline;cis 4 Hydroxyproline;cis-4-Hydroxyproline;Hydroxyproline;Oxyproline

Suppliers and Price of 4-Hydroxyproline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Hydroxyproline

Chemical Property:

Boiling Point:355.2°Cat760mmHg
Flash Point:168.6°C
PSA：69.56000
Density:1.395g/cm³
LogP:-0.87740
XLogP3:-3.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:131.058243149
Heavy Atom Count:9
Complexity:125

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Biological Agents -> Amino Acids and Derivatives
Canonical SMILES:C1C(CNC1C(=O)O)O

Technology Process of 4-Hydroxyproline

There total 23 articles about 4-Hydroxyproline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 408539-58-2
2-oxo-5-phthalimidomethyl-tetrahydro-furan-3-carbonitrile

: 618-28-0,30724-02-8
trans-4-hydroxy-D,L-proline

: 49761-17-3,30724-02-8
cis-4-hydroxyproline

Guidance literature:: With sulfuryl dichloride; acetic acid; at 70 ℃; Erhitzen des Reaktionsprodukts mit konz. wss. HCl und Essigsaeure und Erwaermen des danach erhaltenen Reaktionsprodukts mit wss. Ba(OH)2;
DOI:10.1021/ja01630a038

Reference yield:

: 6284-28-2
2-oxo-5-phthalimidomethyl-tetrahydro-furan-3-carboxylic acid ethyl ester

: 618-28-0,30724-02-8
trans-4-hydroxy-D,L-proline

: 49761-17-3,30724-02-8
cis-4-hydroxyproline

Guidance literature:: With sulfuryl dichloride; acetic acid; at 70 ℃; Erhitzen des Reaktionsprodukts mit konz. wss. HCl und Essigsaeure und Erwaermen des danach erhaltenen Reaktionsprodukts mit wss. Ba(OH)2;
DOI:10.1021/ja01630a038