Technology Process of C19H18ClF3N4O2
There total 3 articles about C19H18ClF3N4O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C
2.1: titanium(III) chloride / tetrahydrofuran / 48 h / 20 °C
3.1: tetrahydrofuran / 1 h / 60 °C
3.2: 20 - 60 °C
4.1: triphenylphosphine; caesium carbonate / palladium diacetate / N,N-dimethyl-formamide / 3 h / 100 °C / Inert atmosphere
With
titanium(III) chloride; potassium carbonate; caesium carbonate; triphenylphosphine;
palladium diacetate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrahydrofuran / 1 h / 60 °C
1.2: 20 - 60 °C
2.1: triphenylphosphine; caesium carbonate / palladium diacetate / N,N-dimethyl-formamide / 3 h / 100 °C / Inert atmosphere
With
caesium carbonate; triphenylphosphine;
palladium diacetate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: titanium(III) chloride / tetrahydrofuran / 48 h / 20 °C
2.1: tetrahydrofuran / 1 h / 60 °C
2.2: 20 - 60 °C
3.1: triphenylphosphine; caesium carbonate / palladium diacetate / N,N-dimethyl-formamide / 3 h / 100 °C / Inert atmosphere
With
titanium(III) chloride; caesium carbonate; triphenylphosphine;
palladium diacetate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
