2,2-diethyl-N¹,N³-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide

Base Information

• Chemical Name: 2,2-diethyl-N¹,N³-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide
• CAS No.: 317373-77-6
• Molecular Formula: C₂₃H₃₀N₂O₆
• Molecular Weight: 430.501

Synonyms:2,2-diethyl-N¹,N³-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide

Chemical Property of 2,2-diethyl-N¹,N³-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-diethyl-N¹,N³-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide

There total 1 articles about 2,2-diethyl-N¹,N³-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N1,N3-di{(1R)-1-[4-(benzyloxy)phenyl]-2-hydroxyethyl}-2,2-diethylmanonamide (600738-27-0) → 2,2-diethyl-N1,N3-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide (317373-77-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 18h; under 3750.38 Torr;

DOI:10.1002/ejoc.200600827

Reference yield: 90.0%

2,2-diethyl-N1,N3-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide (317373-77-6) → N1,N3-bis[(R)-1-(chloromethyl)-2-(4-hydroxyphenyl)ethyl]-2,2-diethylmalonamide

Guidance literature:

With thionyl chloride; In dichloromethane; at 20 ℃; for 18h;

DOI:10.1002/ejoc.200600827

Reference yield: 64.0%

1,4-dibromo-butane (110-52-1) + 2,2-diethyl-N1,N3-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide (317373-77-6) → N1,N3-bis{(R)-1-[4-(4-bromobutoxy)phenyl]-2-hydroxyethyl}-2,2-dithylmalonamide (317373-80-1)

Guidance literature:

With potassium carbonate; In acetonitrile; for 18h; Heating;

DOI:10.1002/ejoc.200600827

upstream raw materials:

N₁,N₃-di{(1R)-1-[4-(benzyloxy)phenyl]-2-hydroxyethyl}-2,2-diethylmanonamide

Downstream raw materials:

N¹,N³-bis{(R)-1-[4-(4-bromobutoxy)phenyl]-2-hydroxyethyl}-2,2-dithylmalonamide

N¹,N³-bis{(R)-1-[4-(5-bromopentyloxy)phenyl]-2-hydroxyethyl}-2,2-dithylmalonamide

N¹,N³-bis{(R)-1-[4-(2-bromoethoxy)phenyl]-2-hydroxyethyl}-2,2-dithylmalonamide

N¹,N³-bis{(R)-1-[4-(3-bromopropoxy)phenyl]-2-hydroxyethyl}-2,2-dithylmalonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 317373-77-6 2,2-diethyl-N¹,N³-bis[(R)-2-hydroxy-1-(4-hydroxyphenyl)ethyl]malonamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send