Technology Process of (E)-4,5-dimethyl-2-styrylphenol
There total 6 articles about (E)-4,5-dimethyl-2-styrylphenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
acetonitrile;
for 16h;
Reflux;
Inert atmosphere;
DOI:10.1002/chem.201706087
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 20 ℃;
for 2h;
DOI:10.1021/ja204924j
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1H-imidazole / tetrahydrofuran / 20 °C / Inert atmosphere
2: N-Bromosuccinimide / dichloromethane
3: water; sodium hydroxide / dichloromethane; N,N-dimethyl-formamide / 20 °C
4: N-[menthyloxycarbonyl]-L-leucine; silver(I) acetate; palladium diacetate; lithium carbonate / 1,2-dichloro-ethane / 24 h / 120 °C / Inert atmosphere
5: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C
With
1H-imidazole; N-Bromosuccinimide; N-[menthyloxycarbonyl]-L-leucine; tetrabutyl ammonium fluoride; water; silver(I) acetate; palladium diacetate; lithium carbonate; sodium hydroxide;
In
tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1021/ja204924j
