(1R,3S)-benzyl 3-((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

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Chemical Name:(1R,3S)-benzyl 3-((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS No.:1240163-25-0
Molecular Formula:C₃₁H₃₄N₂O₅
Molecular Weight:514.621
Hs Code.:

Synonyms:(1R,3S)-benzyl 3-((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

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Chemical Property of (1R,3S)-benzyl 3-((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

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Technology Process of (1R,3S)-benzyl 3-((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

There total 1 articles about (1R,3S)-benzyl 3-((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1240163-19-2
(1R,3S)-benzyl 3-((S)-1-hydroxy-3-methylbutan-2-ylcarbamoyl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

: 1240163-25-0
(1R,3S)-benzyl 3-((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.tetasy.2010.04.053

Reference yield: 59.0%

: 1240163-25-0
(1R,3S)-benzyl 3-((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

: 1240163-33-0
(R)-2-((1R,3S)-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinolin-3-yl)-4-isopropyl-4,5-dihydrooxazole

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 6h; under 760.051 Torr;
DOI:10.1016/j.tetasy.2010.04.053