C₃₂H₄₈O₄Sn

Base Information

• Chemical Name: C₃₂H₄₈O₄Sn
• CAS No.: 1383569-22-9
• Molecular Formula: C₃₂H₄₈O₄Sn
• Molecular Weight: 615.441
• Mol file: 1383569-22-9.mol

Synonyms:C₃₂H₄₈O₄Sn

Chemical Property of C₃₂H₄₈O₄Sn

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₂H₄₈O₄Sn

There total 5 articles about C₃₂H₄₈O₄Sn which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

2-[4-(4-iodobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester (1383569-21-8) + bis(tri-n-butyltin) (813-19-4) → C32H48O4Sn (1383569-22-9)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; at 100 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.ijpharm.2012.04.039

Reference yield:

(4-iodophenyl)(4-methoxyphenyl)methanone (54118-73-9) → C32H48O4Sn (1383569-22-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: aluminum (III) chloride / toluene / 1 h / 100 °C

1.2: 20 °C

2.1: magnesium sulfate; potassium carbonate / N,N-dimethyl-formamide / 10 h / 75 °C

3.1: bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 3 h / 100 °C / Inert atmosphere

With aluminum (III) chloride; bis-triphenylphosphine-palladium(II) chloride; magnesium sulfate; potassium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide; toluene; 2.1: Williamson synthesis;

DOI:10.1016/j.ijpharm.2012.04.039

Reference yield:

4-iodobenzoic acid chloride (1711-02-0) → C32H48O4Sn (1383569-22-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: aluminum (III) chloride / dichloromethane / 4.37 h / 0 - 20 °C

2.1: aluminum (III) chloride / toluene / 1 h / 100 °C

2.2: 20 °C

3.1: magnesium sulfate; potassium carbonate / N,N-dimethyl-formamide / 10 h / 75 °C

4.1: bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 3 h / 100 °C / Inert atmosphere

With aluminum (III) chloride; bis-triphenylphosphine-palladium(II) chloride; magnesium sulfate; potassium carbonate; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; toluene; 1.1: Friedel Crafts acylation / 3.1: Williamson synthesis;

DOI:10.1016/j.ijpharm.2012.04.039

upstream raw materials:

2-[4-(4-iodobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester

bis(tri-n-butyltin)

4-iodobenzoic acid

(4-iodophenyl)(4-methoxyphenyl)methanone

Downstream raw materials:

C₂₀H₂₁⁽¹²⁵⁾IO₄

C₂₀H₂₁⁽¹³¹⁾IO₄