2-{[bis(benzyloxy)phosphoryl]oxy}-1-({[bis(benzyloxy)phosphoryl]oxy}methyl)ethyl (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl carbonate

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Chemical Name:2-{[bis(benzyloxy)phosphoryl]oxy}-1-({[bis(benzyloxy)phosphoryl]oxy}methyl)ethyl (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl carbonate
CAS No.:1220703-59-2
Molecular Formula:C₆₆H₆₇F₁₀NO₁₄P₂
Molecular Weight:1350.19
Hs Code.:

2-{[bis(benzyloxy)phosphoryl]oxy}-1-({[bis(benzyloxy)phosphoryl]oxy}methyl)ethyl (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl carbonate

Synonyms:2-{[bis(benzyloxy)phosphoryl]oxy}-1-({[bis(benzyloxy)phosphoryl]oxy}methyl)ethyl (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl carbonate

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Chemical Property of 2-{[bis(benzyloxy)phosphoryl]oxy}-1-({[bis(benzyloxy)phosphoryl]oxy}methyl)ethyl (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl carbonate

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Technology Process of 2-{[bis(benzyloxy)phosphoryl]oxy}-1-({[bis(benzyloxy)phosphoryl]oxy}methyl)ethyl (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl carbonate

There total 1 articles about 2-{[bis(benzyloxy)phosphoryl]oxy}-1-({[bis(benzyloxy)phosphoryl]oxy}methyl)ethyl (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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: 1220703-58-1
(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl 2-hydroxy-1-(hydroxymethyl)ethyl carbonate

: 108549-23-1
Dibenzyl N,N-diisopropylphosphoramidite

: 1220703-59-2
2-{[bis(benzyloxy)phosphoryl]oxy}-1-({[bis(benzyloxy)phosphoryl]oxy}methyl)ethyl (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl carbonate

Guidance literature:: (1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-((tert-butoxycarbonyl){[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl}amino)propyl 2-hydroxy-1-(hydroxymethyl)ethyl carbonate; Dibenzyl N,N-diisopropylphosphoramidite; With 1H-tetrazole; In dichloromethane; acetonitrile; at 25 ℃; for 3h; Inert atmosphere;

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; acetonitrile; at 0 ℃; for 1h;