(S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile

Base Information

Chemical Name:(S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile
CAS No.:144864-56-2
Molecular Formula:C₁₂H₁₄FNO₂S
Molecular Weight:255.313
Hs Code.:

Synonyms:(S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile

Suppliers and Price of (S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile

There total 3 articles about (S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 143-33-9,25596-52-5
sodium cyanide

: 144864-44-8
(S)-2-(fluoromethyl)-2-(<(R)-(4-methylphenyl)sulfinyl>methyl)oxirane

: 144864-56-2
(S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile

Guidance literature:: With lithium perchlorate; In acetonitrile; at 60 ℃; for 0.75h;
DOI:10.1016/0040-4020(95)00430-G

Reference yield: 65.0%

: 144864-44-8
(S)-2-(fluoromethyl)-2-(<(R)-(4-methylphenyl)sulfinyl>methyl)oxirane

: 144864-56-2
(S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile

Guidance literature:: lithium perchlorate; In acetonitrile;
DOI:10.1016/S0040-4039(00)61160-7

Reference yield:

: 105984-80-3
(+)-(R)-1-fluoro-3-<(4-methylphenyl)sulfinyl>-2-propanone

: 144864-56-2
(S)-4-fluoro-3-hydroxy-3-(<(R)-(4-methylphenyl)sulfinyl>methyl)butanenitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 71.6 percent / diethyl ether / 5 h

2: 65 percent / LiClO₄ / acetonitrile

lithium perchlorate; In diethyl ether; acetonitrile;
DOI:10.1016/S0040-4039(00)61160-7