N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine

Base Information

• Chemical Name: N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine
• CAS No.: 169061-79-4
• Molecular Formula: C₃₃H₃₅Cl₃N₂O₁₄
• Molecular Weight: 790.005

Synonyms:N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine

Chemical Property of N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine

There total 1 articles about N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose (122210-05-3) + N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine (73724-45-5) → Nα-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine (169061-79-4)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; for 5h; Ambient temperature;

DOI:10.1016/0040-4020(95)00224-V

Reference yield:

Nα-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine (169061-79-4) → Nα-(9-flourenylmethoxycarbonyl)-3-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-Β-D-glucopyranosyl)-L-serine (160067-63-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Zn, AcOH / 4 h / Ambient temperature

2: Et₃N / dioxane / 2 h / Ambient temperature

With acetic acid; triethylamine; zinc; In 1,4-dioxane;

DOI:10.1016/0008-6215(95)00016-M

Reference yield:

Nα-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine (169061-79-4) → Nα-(9-flourenylmethoxycarbonyl)-3-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-Β-D-glucopyranosyl)-L-serine (160067-63-0) + Nα-(9-fluorenylmethoxycarbonyl)-3-O-(2-amino-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl)-L-serine 1,2'-lactam

Guidance literature:

With acetic anhydride; acetic acid; zinc; Yield given. Multistep reaction. Yields of byproduct given; 1.) room t., 8.5 h; 2.) 13 h;

DOI:10.1016/0040-4020(95)00224-V

upstream raw materials:

1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose

N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine

Downstream raw materials:

N^α-(9-flourenylmethoxycarbonyl)-3-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-Β-D-glucopyranosyl)-L-serine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 169061-79-4 N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine

Send

Send

Metric Ton KG G Pound L ML

Send

Send