2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester

Base Information

• Chemical Name: 2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester
• CAS No.: 955245-22-4
• Molecular Formula: C₁₅H₁₈N₂O₄S₂
• Molecular Weight: 354.451
• Mol file: 955245-22-4.mol

Synonyms:2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester

Chemical Property of 2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester

There total 1 articles about 2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C14H16N2O4S2 (313230-18-1) + dimethyl sulfate (77-78-1) → 2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester (955245-22-4)

Guidance literature:

C₁₄H₁₆N₂O₄S₂; With potassium hydroxide; In water; at 0 ℃;

dimethyl sulfate; In water; at 20 - 25 ℃; for 24h;

DOI:10.1515/hc-2013-0055

Reference yield: 79.0%

2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester (955245-22-4) → 2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid hydrazide

Guidance literature:

With hydrazine hydrate; at 20 ℃; for 48h;

DOI:10.1515/hc-2013-0055

Reference yield:

2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid ethyl ester (955245-22-4) → 2-(4-methylbenzenesulfonylimino)-3,4-dimethyl-5-(5-methylsulfanyl-[1,3,4]oxadiazol-2-yl)-2,3-dihydrothiazole

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / 48 h / 20 °C

2: potassium hydroxide / ethanol / 7 h / Reflux

3: potassium hydroxide / water / 24 h / 20 °C

With hydrazine hydrate; potassium hydroxide; In ethanol; water;

DOI:10.1515/hc-2013-0055

upstream raw materials:

C₁₄H₁₆N₂O₄S₂

dimethyl sulfate