2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate

Base Information

Chemical Name:2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate
CAS No.:1362689-49-3
Molecular Formula:C₂₅H₁₈F₄N₂O₅S
Molecular Weight:534.488
Hs Code.:

Synonyms:2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate

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Chemical Property of 2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate

Chemical Property:

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Technology Process of 2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate

There total 4 articles about 2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 358-23-6
trifluoromethylsulfonic anhydride

: 1362689-20-0
2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinolin-4-amine

: 1362689-49-3
2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate

Guidance literature:: In pyridine; dichloromethane; at 0 - 20 ℃;

Reference yield:

: 7292-73-1
(2RS)-N-(p-fluorophenyl)glycine

: 1362689-49-3
2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: hexane; tetrahydrofuran / 4 h / -20 - 50 °C

2.1: 4-methyl-morpholine / tetrahydrofuran / -25 - 20 °C

3.1: tetrahydrofuran / 50 - 70 °C

3.2: 65 - 100 °C

4.1: dichloromethane; pyridine / 0 - 20 °C

With 4-methyl-morpholine; In tetrahydrofuran; pyridine; hexane; dichloromethane;

Reference yield:

: 4-(4-fluorophenyl)oxazolidine-2,5-dione

: 1362689-49-3
2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)quinolin-4-yl trifluormethanesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 4-methyl-morpholine / tetrahydrofuran / -25 - 20 °C

2.1: tetrahydrofuran / 50 - 70 °C

2.2: 65 - 100 °C

3.1: dichloromethane; pyridine / 0 - 20 °C

With 4-methyl-morpholine; In tetrahydrofuran; pyridine; dichloromethane;