C₄₂H₄₇F₃N₈O₇

Base Information

• Chemical Name: C₄₂H₄₇F₃N₈O₇
• CAS No.: 1258507-36-6
• Molecular Formula: C₄₂H₄₇F₃N₈O₇
• Molecular Weight: 832.88
• Mol file: 1258507-36-6.mol

Synonyms:C₄₂H₄₇F₃N₈O₇

Chemical Property of C₄₂H₄₇F₃N₈O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₄₇F₃N₈O₇

There total 5 articles about C₄₂H₄₇F₃N₈O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C47H55F3N8O9 → C42H47F3N8O7 (1258507-36-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1016/j.chembiol.2010.01.008

Reference yield:

2-(4-Aminophenoxy)ethylcarbamic acid 1,1-dimethylethyl ester (159184-15-3) → C42H47F3N8O7 (1258507-36-6)

Guidance literature:

Multi-step reaction with 5 steps

1: ethanol / 80 °C

2: triethylamine; trifluoroacetic acid / dimethyl sulfoxide / 95 °C

3: trifluoroacetic acid / dichloromethane / 20 °C

4: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

5: trifluoroacetic acid / dichloromethane / 20 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In ethanol; dichloromethane; dimethyl sulfoxide;

DOI:10.1016/j.chembiol.2010.01.008

Reference yield:

C22H24ClN5O3 (1258507-28-6) → C42H47F3N8O7 (1258507-36-6)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine; trifluoroacetic acid / dimethyl sulfoxide / 95 °C

2: trifluoroacetic acid / dichloromethane / 20 °C

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

4: trifluoroacetic acid / dichloromethane / 20 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; dimethyl sulfoxide;

DOI:10.1016/j.chembiol.2010.01.008

upstream raw materials:

2-(4-Aminophenoxy)ethylcarbamic acid 1,1-dimethylethyl ester

C₂₂H₂₄ClN₅O₃

C₃₇H₃₆F₃N₇O₄

4-chloro-6-(2-chloropyridin-3-yl)pyrimidine