3-[2-(2-fluoro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester

Base Information

Chemical Name:3-[2-(2-fluoro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester
CAS No.:1054598-67-2
Molecular Formula:C₁₈H₁₆FNO₂S
Molecular Weight:329.395
Hs Code.:

Synonyms:3-[2-(2-fluoro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester

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Chemical Property of 3-[2-(2-fluoro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester

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Technology Process of 3-[2-(2-fluoro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester

There total 1 articles about 3-[2-(2-fluoro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 5548-09-4
Methyl indole-3-propionate

: 2-fluorobenzenesulfenyl chloride

: 1054598-67-2
3-[2-(2-fluoro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester

Guidance literature:: In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1002/anie.200801336

Reference yield:

: 4-chloro-2-diazo-but-3-enoic acid ethyl ester

: 1054598-67-2
3-[2-(2-fluoro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester

: ethyl (2E)-4-chloro-4-[2-[(2-fluorophenyl)thio]-3-(3-methoxy-3-oxopropyl)-3H-indol-3-yl]but-2-enoate

: ethyl (2E)-4-chloro-4-[2-[(2-fluorophenyl)thio]-3-(3-methoxy-3-oxopropyl)-3H-indol-3-yl]but-2-enoate

Guidance literature:: With dirhodium tetraacetate; In dichloromethane; at 20 ℃; for 3h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1002/anie.200801336