4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide

Base Information

Chemical Name:4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide
CAS No.:1448859-91-3
Molecular Formula:C₂₇H₂₃IN₂O₂
Molecular Weight:534.396
Hs Code.:

Synonyms:4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide

Suppliers and Price of 4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide

There total 4 articles about 4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1448859-81-1
4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid

: 696-40-2
3-iodobenzylamine

: 1448859-91-3
4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide

Guidance literature:: 4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid; With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

3-iodobenzylamine; With 4-methyl-morpholine; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/jm400947b

Reference yield:

: 4-benzoyl-5-methyl-1H-pyrrole-2-carboxylic acid methyl ester

: 1448859-91-3
4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide; tetra(n-butyl)ammonium hydroxide / dichloromethane; water / 0 - 20 °C

2.1: sodium hydroxide / methanol / Reflux

2.2: pH Ca_. 3

3.1: benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / 0.33 h / 20 °C

3.2: 20 °C

With tetra(n-butyl)ammonium hydroxide; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; sodium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jm400947b

Reference yield:

: 1448859-76-4
4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid methyl ester

: 1448859-91-3
4-benzoyl-1-benzyl-5-methyl-1H-pyrrole-2-carboxylic acid 3-iodobenzylamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / methanol / Reflux

1.2: pH Ca_. 3

2.1: benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / 0.33 h / 20 °C

2.2: 20 °C

With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; sodium hydroxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm400947b