N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

Base Information

Chemical Name:N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester
CAS No.:206753-50-6
Molecular Formula:C₁₆H₂₂N₂O₅
Molecular Weight:322.361
Hs Code.:

Synonyms:N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

Suppliers and Price of N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

There total 1 articles about N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5781-53-3
monomethyl oxalyl chloride

: 24424-99-5
di-tert-butyl dicarbonate

: 1664-40-0
N-(2-aminoethyl)benzeneamine

: 206753-50-6
N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

Guidance literature:: With triethylamine; Yield given. Multistep reaction; 1.) CH₂Cl₂, 0 deg C, 2.) 45 min;
DOI:10.1021/jo9800309

Reference yield: 100.0%

: 206753-50-6
N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

: N-(2-Amino-ethyl)-N-phenyl-oxalamic acid methyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 0 ℃; for 0.05h;
DOI:10.1021/jo9800309

Reference yield:

: 206753-50-6
N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

: N-[2-(Benzyl-butyl-amino)-ethyl]-N-phenyl-oxalamic acid methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 100 percent / HCl gas / ethyl acetate / 0.05 h / 0 °C

2: 72 percent / Na(OAc)3BH, 4A MS / 1,2-dichloro-ethane / 4 h / 0 - 20 °C / tandem reductive alkylation-cyclization of amines with various aldehydes and ketones to give 2m3-diketopiperazines

3: 81 percent / aq. HCl / 5 h / Heating

4: 2.) Et₃N / 1.) CH₂Cl₂, 0 deg C, 2.) 45 min

5: 100 percent / HCl gas / ethyl acetate / 0.5 h / 0 °C

6: 75 percent / Na(OAc)3BH, 4A MS / 1,2-dichloro-ethane / 1.) 0 deg C, 30 min, 2.) room temperature, 4 h

With hydrogenchloride; sodium tris(acetoxy)borohydride; triethylamine; In ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1021/jo9800309