(4S)-4-[(4,4-dimethylcyclohexyl)((S)-tetrahydrofuran-2-ylcarbonyl)amino]-N-ethyl-N-methyl-L-prolineamide

Base Information

Chemical Name:(4S)-4-[(4,4-dimethylcyclohexyl)((S)-tetrahydrofuran-2-ylcarbonyl)amino]-N-ethyl-N-methyl-L-prolineamide
CAS No.:1002728-88-2
Molecular Formula:C₂₁H₃₇N₃O₃
Molecular Weight:379.543
Hs Code.:

Synonyms:(4S)-4-[(4,4-dimethylcyclohexyl)((S)-tetrahydrofuran-2-ylcarbonyl)amino]-N-ethyl-N-methyl-L-prolineamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4S)-4-[(4,4-dimethylcyclohexyl)((S)-tetrahydrofuran-2-ylcarbonyl)amino]-N-ethyl-N-methyl-L-prolineamide

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Technology Process of (4S)-4-[(4,4-dimethylcyclohexyl)((S)-tetrahydrofuran-2-ylcarbonyl)amino]-N-ethyl-N-methyl-L-prolineamide

There total 1 articles about (4S)-4-[(4,4-dimethylcyclohexyl)((S)-tetrahydrofuran-2-ylcarbonyl)amino]-N-ethyl-N-methyl-L-prolineamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.9%

: 1002728-87-1
1-BOC-(2S,4S)-4-{(4,4-dimethylcyclohexyl)[(2S)-tetrahydrofuran-2-ylcarbonyl]amino}-2-{[ethyl(methyl)amino]carbonyl}pyrrolidine

: 1002728-88-2
(4S)-4-[(4,4-dimethylcyclohexyl)((S)-tetrahydrofuran-2-ylcarbonyl)amino]-N-ethyl-N-methyl-L-prolineamide

Guidance literature:: With hydrogenchloride; water; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 85.0%

: 1002728-89-3
(3S,4R)-1-t-butyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid

: 1002728-88-2
(4S)-4-[(4,4-dimethylcyclohexyl)((S)-tetrahydrofuran-2-ylcarbonyl)amino]-N-ethyl-N-methyl-L-prolineamide

: (4S)-1-{[(3S,4R)-1-tert-butyl-4-(4-chlorophenyl)pyrrolidine-3-yl]carbonyl}-4-{(4,4-dimethylcyclohexyl)[(2S)-tetrahydrofuran-2-ylcarbonyl]amino}-N,N-ethylmethyl-L-prolineamide trifluoroacetate

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h;