2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines

Base Information

Chemical Name:2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines
CAS No.:808134-47-6
Molecular Formula:C₁₆H₁₆N₂O₂S
Molecular Weight:300.381
Hs Code.:

Synonyms:2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines

Chemical Property:

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Technology Process of 2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines

There total 6 articles about 2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143703-45-1
2-[1-(benzenesulfonyl)indol-3-yl]acetonitrile

: 808134-47-6
2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines

Guidance literature:: With hydrogen; nickel; In ethanol; for 2h; under 1810.02 Torr;

Reference yield:

: C₂₁H₂₄N₂O₄S

: 808134-47-6
2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm070521y

Reference yield:

: 83-34-1
3-Methylindole

: 808134-47-6
2-[1-(phenylsulfonyl)-1H-indol-3-yl]ethanamines

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) dimsyl sodium

2: 96 percent / NBS, benzoyl peroxide / CCl₄ / 6 h / Heating

3: 96 percent / tetrahydrofuran; dimethylsulfoxide / 12 h / Ambient temperature

4: H₂ / Raney nickel / ethanol / 2 h / 1810.02 Torr

With N-Bromosuccinimide; Perbenzoic acid; hydrogen; sodium methylsulfinylmethanide; nickel; In tetrahydrofuran; tetrachloromethane; ethanol; dimethyl sulfoxide;