1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-(2,4-dichloroanilino)-3-methyl-

Base Information

Chemical Name:1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-(2,4-dichloroanilino)-3-methyl-
CAS No.:86831-74-5
Molecular Formula:C₁₂H₉Cl₂N₅O
Molecular Weight:310.142
Hs Code.:
DSSTox Substance ID:DTXSID20235852
Nikkaji Number:J66.492H
Wikidata:Q83117760

Synonyms:6-(2,4-Dichloroanilino)-3-methyl-1H-pyrazolo(4,3-d)pyrimidin-7(6H)-one;1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-(2,4-dichloroanilino)-3-methyl-;86831-74-5;7H-Pyrazolo(4,3-d)pyrimidin-7-one, 6-((2,4-dichlorophenyl)amino)-1,6-dihydro-3-methyl-;6-(2,4-Dichloroanilino)-3-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one;C12H9Cl2N5O;DTXSID20235852;LS-129284

Suppliers and Price of 1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-(2,4-dichloroanilino)-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-(2,4-dichloroanilino)-3-methyl-

Chemical Property:

Vapor Pressure:8.34E-12mmHg at 25°C
Boiling Point:541.9°C at 760 mmHg
Flash Point:281.5°C
Density:1.67g/cm³
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:309.0184153
Heavy Atom Count:20
Complexity:421

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=NN1)C(=O)N(C=N2)NC3=C(C=C(C=C3)Cl)Cl

Technology Process of 1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-(2,4-dichloroanilino)-3-methyl-

There total 4 articles about 1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-(2,4-dichloroanilino)-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 86831-71-2
4-Amino-5-methyl-2H-pyrazole-3-carboxylic acid N'-(2,4-dichloro-phenyl)-hydrazide

: 86831-74-5
6-(2,4-Dichloro-phenylamino)-3-methyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one

Guidance literature:: at 180 ℃; for 5h;

Reference yield:

: 80030-73-5
2,7-dimethyl-3,8-dinitrodipyrazolo[1,5-a;1',5'-d]pyrazine-4,9-dione

: 86831-74-5
6-(2,4-Dichloro-phenylamino)-3-methyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one

Guidance literature:: Multi-step reaction with 3 steps

1: 72 percent

2: 62 percent / NH₂NH₂*H₂O / Pd/C

3: 62 percent / 5 h / 180 °C

With hydrazine hydrate; palladium on activated charcoal;

Reference yield:

: 86831-68-7
5-Methyl-4-nitro-2H-pyrazole-3-carboxylic acid N'-(2,4-dichloro-phenyl)-hydrazide

: 86831-74-5
6-(2,4-Dichloro-phenylamino)-3-methyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / NH₂NH₂*H₂O / Pd/C

2: 62 percent / 5 h / 180 °C

With hydrazine hydrate; palladium on activated charcoal;