2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester

Base Information

• Chemical Name: 2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester
• CAS No.: 1238062-20-8
• Molecular Formula: C₂₉H₃₁N₃O₆
• Molecular Weight: 517.582

Synonyms:2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester

Chemical Property of 2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester

There total 1 articles about 2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

6-carbocxylic acid methyl ester-1-(tert-butoxycarbonyl)-1H-indol-2-ylboronic acid (848357-46-0) + 3-iodo-4-phenyl-pyrazole-1-carboxylic acid tert-butyl ester (1238062-19-5) → 2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester (1238062-20-8)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In 1,4-dioxane; at 80 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.bmc.2010.04.056

Reference yield: 97.0%

2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester (1238062-20-8) → 2-(4-phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylic acid methyl ester (1238062-60-6)

Guidance literature:

With water; potassium hydroxide; In methanol; at 20 ℃; for 3h;

DOI:10.1016/j.bmc.2010.04.056

Reference yield: 64.0%

2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester (1238062-20-8) → 2-(4-phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylic acid (1238062-21-9)

Guidance literature:

With water; potassium hydroxide; In methanol; for 12h; Reflux;

DOI:10.1016/j.bmc.2010.04.056

upstream raw materials:

6-carbocxylic acid methyl ester-1-(tert-butoxycarbonyl)-1H-indol-2-ylboronic acid

3-iodo-4-phenyl-pyrazole-1-carboxylic acid tert-butyl ester

Downstream raw materials:

2-(4-phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylic acid methyl ester

2-(4-phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1238062-20-8 2-(1-tert-butoxycarbonyl-4-phenyl-1H-pyrazol-3-yl)-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send