(+)-(R)-oleuropeic acid

Base Information

• Chemical Name: (+)-(R)-oleuropeic acid
• CAS No.: 22155-73-3
• Molecular Formula: C₁₀H₁₆O₃
• Molecular Weight: 184.235

Synonyms:(+)-(R)-oleuropeic acid

Chemical Property of (+)-(R)-oleuropeic acid

Chemical Property:

Purity/Quality:

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Technology Process of (+)-(R)-oleuropeic acid

There total 6 articles about (+)-(R)-oleuropeic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.9%

4R-α-terpineol (7785-53-7,2438-12-2) → (+)-(R)-oleuropeic acid (22155-73-3) + (1S,2R,4R)-p-menthane-1,2,8-triol (93861-30-4)

Guidance literature:

With strain of Alternaria alternata; In methanol; for 168h; Reagent/catalyst; Microbiological reaction;

DOI:10.1039/c9ra08042b

Reference yield:

6-O-[(R)-oleuropeoyl]-1-O-[2-(1-hydroxy-4-oxo-2,5-cyclohexadien-1-yl)ethyl]-β-D-glucopyranose (1616079-03-8) → (+)-(R)-oleuropeic acid (22155-73-3)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 12h;

DOI:10.1016/j.phytochem.2014.04.010

Reference yield:

6-O-[(R)-oleuropeoyl]-1-O-[2-(1-hydroxy-4-oxocyclohexyl)ethyl]-β-D-glucopyranose (1616079-04-9) → (+)-(R)-oleuropeic acid (22155-73-3)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 12h;

DOI:10.1016/j.phytochem.2014.04.010

upstream raw materials:

8-bromo-p-menth-1-en-7-oic acid

1,6-di-O-[(R)-oleuropeyl]-β-D-glucopyranose

6-O-[(R)-oleuropeoyl]-1-O-[2-(1-hydroxy-4-oxo-2,5-cyclohexadien-1-yl)ethyl]-β-D-glucopyranose

6-O-[(R)-oleuropeoyl]-1-O-[2-(1-hydroxy-4-oxocyclohexyl)ethyl]-β-D-glucopyranose

Downstream raw materials:

cypellocarpin C

1,6-di-O-[(R)-oleuropeyl]-β-D-glucopyranose

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