1-(4-Benzyl-2-methyl-1,3-oxazol-5-yl)piperidine

Base Information

Chemical Name:1-(4-Benzyl-2-methyl-1,3-oxazol-5-yl)piperidine
CAS No.:144760-78-1
Molecular Formula:C₁₆H₂₀N₂O
Molecular Weight:256.348
Hs Code.:
DSSTox Substance ID:DTXSID001226805
Nikkaji Number:J494.749E

Synonyms:1-(4-benzyl-2-methyl-1,3-oxazol-5-yl)piperidine;DTXSID001226805;AKOS015905152;144760-78-1;1-(4-benzyl-2-methyl-oxazol-5-yl)-piperidine;1-[2-Methyl-4-(phenylmethyl)-5-oxazolyl]piperidine

Suppliers and Price of 1-(4-Benzyl-2-methyl-1,3-oxazol-5-yl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-Benzyl-2-methyl-1,3-oxazol-5-yl)piperidine

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:256.157563266
Heavy Atom Count:19
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NC(=C(O1)N2CCCCC2)CC3=CC=CC=C3

Technology Process of 1-(4-Benzyl-2-methyl-1,3-oxazol-5-yl)piperidine

There total 3 articles about 1-(4-Benzyl-2-methyl-1,3-oxazol-5-yl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 144760-73-6
N-(1-Benzyl-2-oxo-2-piperidin-1-yl-ethyl)-acetamide

: 144760-78-1
1-(4-Benzyl-2-methyl-oxazol-5-yl)-piperidine

Guidance literature:: With triethylamine; dibromotriphenylphosphorane; In dichloromethane; 1.) reflux, 0.5 h, 2.) r.t., 12 h;
DOI:10.1055/s-1992-26270

Reference yield:

: 110-89-4
piperidine

: 144760-78-1
1-(4-Benzyl-2-methyl-oxazol-5-yl)-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) dicyclohexylcarbodiimide / 1.) CH₂Cl₂, r.t., 1 h, 2.) r.t.

2: 97 percent / dibromotriphenylphosphorane, Et₃N / CH₂Cl₂ / 1.) reflux, 0.5 h, 2.) r.t., 12 h

With triethylamine; dicyclohexyl-carbodiimide; dibromotriphenylphosphorane; In dichloromethane;
DOI:10.1055/s-1992-26270

Reference yield:

: 2901-75-9
(R,S)-N-acetyl phenylalanine

: 144760-78-1
1-(4-Benzyl-2-methyl-oxazol-5-yl)-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) dicyclohexylcarbodiimide / 1.) CH₂Cl₂, r.t., 1 h, 2.) r.t.

2: 97 percent / dibromotriphenylphosphorane, Et₃N / CH₂Cl₂ / 1.) reflux, 0.5 h, 2.) r.t., 12 h

With triethylamine; dicyclohexyl-carbodiimide; dibromotriphenylphosphorane; In dichloromethane;
DOI:10.1055/s-1992-26270