OseltaMivir Acid Hydrochloride

Base Information

Chemical Name:OseltaMivir Acid Hydrochloride
CAS No.:1415963-60-8
Molecular Formula:C₁₄H₂₄N₂O₄*ClH
Molecular Weight:320.816
Hs Code.:
Mol file:1415963-60-8.mol

Synonyms:(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid hydrochloride

Suppliers and Price of OseltaMivir Acid Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
OseltamivirAcidHydrochloride
10mg
$ 215.00

TRC
OseltamivirAcidHydrochloride
2.5mg
$ 120.00

Medical Isotopes, Inc.
OseltamivirAcidHCl
25 mg
$ 2400.00

Total 10 raw suppliers

Chemical Property of OseltaMivir Acid Hydrochloride

Chemical Property:

Melting Point:>158°C (dec.)
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

≥95% ^*data from raw suppliers

OseltamivirAcidHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Oseltamivir Acid Hydrochloride is a metabolite of Oseltamivir (O701000), an orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug. It is a COVID19-related research product.

Technology Process of OseltaMivir Acid Hydrochloride

There total 2 articles about OseltaMivir Acid Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.2%

: 764639-63-6
(3R,4R,5S)-4-acetamido-5-[(tert-butoxycarbonyl)-amino]-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid

: 1415963-60-8
(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid hydrochloride

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 20 ℃;
DOI:10.1007/s00044-012-0341-2

Reference yield:

: 204255-11-8
oseltamivir phosphate

: 1415963-60-8
(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / tetrahydrofuran; water / 6 h / 20 °C

1.2: 1 h / 20 °C

2.1: hydrogenchloride / ethyl acetate / 20 °C

With hydrogenchloride; sodium hydrogencarbonate; In tetrahydrofuran; water; ethyl acetate;
DOI:10.1007/s00044-012-0341-2