2-Bromo-4-methoxy-3-(methoxymethoxy)benzaldehyde

Base Information

Chemical Name:2-Bromo-4-methoxy-3-(methoxymethoxy)benzaldehyde
CAS No.:115961-42-7
Molecular Formula:C₁₀H₁₁BrO₄
Molecular Weight:275.099
Hs Code.:
DSSTox Substance ID:DTXSID601237919

Synonyms:2-bromo-4-methoxy-3-(methoxymethoxy)benzaldehyde;115961-42-7;DTXSID601237919

Suppliers and Price of 2-Bromo-4-methoxy-3-(methoxymethoxy)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-Bromo-4-methoxy-3-(methoxymethoxy)benzaldehyde

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:273.98407
Heavy Atom Count:15
Complexity:200

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COCOC1=C(C=CC(=C1Br)C=O)OC

Technology Process of 2-Bromo-4-methoxy-3-(methoxymethoxy)benzaldehyde

There total 3 articles about 2-Bromo-4-methoxy-3-(methoxymethoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 621-59-0
isovanillin

: 115961-42-7
2-bromo-3-(methoxymethoxy)-4-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / Br₂, NaOAc, HOAc / 2 h / 25 °C

2: 80 percent / NaH / dimethylformamide / 18 h / 25 °C

With bromine; sodium acetate; sodium hydride; acetic acid; In N,N-dimethyl-formamide;
DOI:10.1021/jo00379a038

Reference yield:

: 1315614-02-8
tert-butyl 2-((5aS,9aS)-1-((1,3-dioxolan-2-yl)methyl)-4-methoxy-6-oxo-5a,6,9,9a-tetrahydrodibenzo[b,d]furan-9a-yl)ethyl(methyl)carbamate

: 115961-42-7
2-bromo-3-(methoxymethoxy)-4-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid / dichloromethane / 1 h / Inert atmosphere

2: water / acetonitrile / Inert atmosphere; Acidic conditions

3: N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 0 °C / Inert atmosphere

With water; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; acetonitrile;
DOI:10.1139/v11-071

Reference yield:

: 1315614-03-9
(4S, 6aS, 11bR)-11-(1,3-dioxolan-2-ylmethyl)-8-methoxy-3-methyl-2,3,4,5-tetra-hydro-1H-4,11b-methano[1]benzofuro[3,2-d]azocin-6-one

: 115961-42-7
2-bromo-3-(methoxymethoxy)-4-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: water / acetonitrile / Inert atmosphere; Acidic conditions

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 0 °C / Inert atmosphere

With water; N-ethyl-N,N-diisopropylamine; In dichloromethane; acetonitrile;
DOI:10.1139/v11-071